Fig. 12. Cd-induced Akt activation is implicated in migration. HT-29 cells were treated with Cd (100 nM) in the presence or absence of LY294 002 (10 µM), a PI3K inhibitor and/or CLX. Migration was evaluated using scratch wound healing assay. Values are represented as mean ± SEM of n=3.* denotes p<0.05.